Picture of Stolla
Assistant Professor of Medicine, Division of Hematology
University of Washington School of Medicine
Director, Platelet Transfusion Research, Bloodworks NW Research Institute
Assistant Member, Bloodworks NW Research Institute
Associate Medical Director, Swedish Medical Center, Blood Transfusion Service

Faculty Information

Biography

Dr. Stolla is a physician scientist with a clinical background in internal medicine and clinical pathology. His research background is in platelet transfusion, vascular biology, and thrombosis/hemostasis.

A major focus of Dr. Stolla’s research is to improve platelet transfusions and to evaluate alternative platelet products. It is very difficult to supply platelet products to far-forward combat casualty care facilities and remote civilian hospital locations. Presently, most Blood Banks in the U.S. store their platelets at room temperature under gentle agitation with a maximum storage time of 5 days since bacterial growth and septic reactions increase over time. This limited shelf-life leads to periodic shortages on the one hand and frequent outdates on the other. Contrary to red cells, platelet demand has slightly increased according to recently published data. Previous studies revealed that storing platelets in the cold (4ºC) leads to a significant reduction in platelet survivals compared with room temperature-stored platelets (RTP). In vitro studies suggest that 4ºC-stored platelets have superior function compared with room temperature-stored platelets. Furthermore, storage of platelets in the cold (4ºC) has the advantage of potentially prolonging storage times while reducing post-transfusion infections. Having a second inventory with extended storage in the cold (e.g., up to 15 days) for specifically targeted patient populations could lead to both greater platelet availability and fewer outdates. Dr. Stolla’s lab is determining how long and in which storage solution platelets can be stored at 4°C to maintain adequate post-storage viability and function. In addition, he is working on improving frozen, lyophilized and pathogen-reduced platelets for transfusion.

Education & Training: 
M.D.
Ludwig-Maximilians-University
Munich, Germany
2000-2006
Doctorate
Technical University
Munich, Germany
2004-2008
Internship
Internal Medicine
Munich, Germany
2006-2008
Postdoc
Cardeza Foundation, Thomas Jefferson University
Munich, Germany
2009-2012
Residency in Pathology
University of Rochester
Rochester, NY
2012-2015
Fellowship in Transfusion Medicine
Joint Program Harvard Medical School
Boston, MA
2015-2016