johnsen_jill
Associate Professor, Division of Hematology
University of Washington
Associate Member, Bloodworks NW Research Institute

Faculty Information

Biography

Dr. Johnsen is a physician scientist with expertise in classical (benign) hematology.  Her research laboratory is located in the Bloodworks Research Institute, and she sees patients at the Washington Center for Bleeding Disorders (WACBD) at the Washington Institute for Coagulation (WIC).

Dr. Johnsen studies the genetics and biology of variation in clotting factors and blood groups (blood types), with emphasis on coagulation factor VIII (FVIII), factor IX (FIX), and von Willebrand factor (VWF), and clinically relevant blood group genes, particularly the ABO and Rh systems. Dr. Johnsen is particularly interested to leverage these research efforts towards better understanding how bleeding uniquely impacts females.

Dr. Johnsen’s research program is dedicated to improving the diagnosis and care of patients with blood disorders through advancement of our basic understanding of the underlying biology and through the translation of new knowledge and laboratory innovations to improve clinical testing.  Her research leverages new technologies, including targeted and whole genome next generation DNA sequencing, multi-omics, long-read sequencing, and new and novel molecular methods. In vitro functional studies, including large scale deep mutational scanning of genes of interest in mammalian cell display systems, will inform and improve interpretation of the functional significance of DNA variants discovered in hemophilia.

Education & Training: 
B.A. in Microbiology
Miami University
Oxford, OH
1990-1994
M.D.
Case Western Reserve University School of Medicine
Cleveland, OH
1994-1998
Internship/Residency in Internal Medicine
University Hospitals of Cleveland
Cleveland, OH
1997-2000
Fellowship in Hematology/Oncology
University of Michigan
Ann Arbor, MI
2000-2003
Lecturer/Postdoctoral Research Fellow in Internal Medicine, Hematology/Oncology
University of Michigan
Ann Arbor, MI
2003-2007
Honors: 
National Merit Scholar
1990
Sigma Xi
1993
Atlas Fund Research Award
1995
Amgen Hematology/Oncology Fellowship Award
2003
Ruth L. Kirschstein NRSA for Individual Postdoctoral Fellows
2004
Judith Graham Pool Postgraduate Research Award (National Hemophilia Foundation)
2004
Internal Medicine Research Day Award, University of Michigan
2005
International Society on Thrombosis and Haemostasis Young Investigator
2005
International Mammalian Genome Society Scholarship Award
2005,2006
National Blood Foundation Scholar
2010
American Society of Hematology Scholar Award Junior Faculty Basic Science
2011
American Society of Hematology Abstract Achievement Award
2011,2012
University of Washington Research Royalty Fund Award
2012
Innovative Investigator Research Award, National Hemophilia Foundation
2017
Hemostasis and Thrombosis Research Society Mid-Career Award
2019
Contact
Mailing Address: 

Phone and FAX: 

Clinic: Washington Center for Bleeding Disorders (WACBD): 206-614-1200

Clinic Website: https://wacbd.org

 

Research Office: 206-568-2230

          Research FAX: (206) 587-6056

 

Email: 

Clinic: For patients and patient-related information: info@wacbd.org

For all time-sensitive clinical issues, please call the WACBD clinic.

 

For research and all other e-mails: jjohnsen@uw.edu

  Alternate e-mail: jillj@bloodworksnw.org

 

Mailing Address: 

Clinic and all patient-related documents:

Washington Center for Bleeding Disorders

701 Pike Street, Suite 1900

Seattle, WA 98101

Research:

Bloodworks Research Institute, c/o Johnsen Lab

1551 Eastlake Avenue East, Suite #100

Seattle, WA  98102

Research & Clinical Interests
Research Interests: 

Genetics of von Willebrand Factor (VWF) and von Willebrand Disease (VWD), factor VIII (FVIII) and hemophilia A, factor IX (FIX) and hemophilia B, and blood group antigens (particularly ABO and Rh).

Variation in blood coagulation (VWF, FVIII, FIX) and bleeding disorders in females, VWF and FVIII changes in pregnancy, female genetic carriers of hemophilia

Development of new laboratory approaches in hematology

Clinical Interests: 

Bleeding disorders including von Willebrand Disease, hemophilia, and rare coagulation disorders.

Publications