Dr. Johnsen is a physician scientist with expertise in classical (benign) hematology. She sees patients in the Washington Center for Bleeding Disorders (WCBD) at Bloodworks Northwest (BWNW). Dr. Johnsen studies the genetics and biology of clotting factors and blood groups (blood types), with emphasis on coagulation factor VIII (FVIII), factor IX (FIX), and von Willebrand factor (VWF), and clinically relevant blood group genes, particularly in the ABO and Rh systems.
Dr. Johnsen’s research takes new next generation sequencing approaches to identify genetic/genomic variation in genes responsible for hemostasis and the expression blood types. These studies have found (and continue to find) a wide variety of simple, complex, rare, and novel DNA changes in coagulation factor and blood group genes. Findings from this work informs functional studies of the consequences of DNA changes in these genes to better understand causes of disease and to improve interpretation of genetic data. Dr. Johnsen is further working to better understand the molecular basis of how inherited bleeding disorders uniquely impact females, particularly in hemophilia and von Willebrand disease.
Phone and FAX:
Clinic at the Washington Center for Bleeding Disorders (WCBD): 206-292-6570
After hours emergencies call (206) 689-6525 and press option 3
Clinic FAX: (206) 689-8341
Research Office: 206-568-2230
Research FAX: (206) 587-6056
Patients and patient-information: firstname.lastname@example.org
For all time-sensitive clinical issues, please call the WCBD clinic (contact information above).
Research and all other e-mails: email@example.com
Alternate e-mail: firstname.lastname@example.org
Washington Center for Bleeding Disorders
921 Terry Avenue
Seattle, WA 98104
1551 Eastlake Avenue East, Suite #100
Seattle, WA 98102
Genetics of von Willebrand Factor (VWF) and von Willebrand Disease (VWD), factor VIII (FVIII) and hemophilia A, factor IX (FIX) and hemophilia B, and blood group antigens (particularly ABO and Rh).
Variation in blood coagulation (VWF, FVIII, FIX) and bleeding disorders in women and girls, VWF and FVIII changes in pregnancy, female genetic carriers of hemophilia
Development of new laboratory approaches in hematology
Disorders of hemostasis including von Willebrand Disease, hemophilia, and platelet disorders.