Associate Professor, Division of HematologyInstitute for Stem Cell & Regenerative Medicine (ISCRM)Center for Cardiovascular Biology (CCB)University of WashingtonFaculty Information Biography Dr. Johnsen is a physician scientist with expertise in classical (benign) hematology. Her research laboratory is located in the UW South Lake Union (SLU) research hub, and she sees patients at the Washington Center for Bleeding Disorders (WACBD) at the Washington Institute for Coagulation (WIC). Dr. Johnsen studies the genetics and biology of variation in clotting factors and blood groups (blood types), with emphasis on coagulation factor VIII (FVIII), factor IX (FIX), and von Willebrand factor (VWF), and clinically relevant blood group genes, particularly the ABO and Rh systems. Dr. Johnsen is particularly interested to leverage these research efforts towards better understanding how bleeding uniquely impacts females. Dr. Johnsen’s research program is dedicated to improving the diagnosis and care of patients with blood disorders through advancement of our basic understanding of the underlying biology and through the translation of new knowledge and laboratory innovations to improve clinical testing. Her research leverages new technologies, including targeted and whole genome next generation DNA sequencing, multi-omics, long-read sequencing, and new and novel molecular methods. In vitro functional studies, including large scale deep mutational scanning of genes of interest in mammalian cell display systems, will inform and improve interpretation of the functional significance of DNA variants discovered in hemophilia. Education & Training: B.A. in MicrobiologyMiami UniversityOxford, OH1990-1994 M.D.Case Western Reserve University School of MedicineCleveland, OH1994-1998 Internship/Residency in Internal MedicineUniversity Hospitals of ClevelandCleveland, OH1997-2000 Fellowship in Hematology/OncologyUniversity of MichiganAnn Arbor, MI2000-2003 Lecturer/Postdoctoral Research Fellow in Internal Medicine, Hematology/OncologyUniversity of MichiganAnn Arbor, MI2003-2007 Honors: National Merit Scholar 1990 Sigma Xi 1993 Atlas Fund Research Award 1995 Amgen Hematology/Oncology Fellowship Award 2003 Ruth L. Kirschstein NRSA for Individual Postdoctoral Fellows 2004 Judith Graham Pool Postgraduate Research Award (National Hemophilia Foundation) 2004 Internal Medicine Research Day Award, University of Michigan2005 International Society on Thrombosis and Haemostasis Young Investigator 2005 International Mammalian Genome Society Scholarship Award 2005,2006 National Blood Foundation Scholar 2010 American Society of Hematology Scholar Award Junior Faculty Basic Science 2011 American Society of Hematology Abstract Achievement Award 2011,2012 University of Washington Research Royalty Fund Award 2012 Innovative Investigator Research Award, National Hemophilia Foundation 2017 Hemostasis and Thrombosis Research Society Mid-Career Award 2019 Contact Email: jjohnsen@uw.eduPhone: (206) 685-8832Mailing Address: 850 Republican StBrotman Building, RM 331University of WashingtonSeattle, WA 98109 Please contact the Washington Center for Bleeding Disorders (WACBD) for clinical matters Phone:206-614-1200 Address:710 Pike Street, Suite 1900Seattle, WA 98101 WACBD Email: info@wacbd.org WACBD Website: https://wacbd.org Research & Clinical Interests Research Interests: Genetics of von Willebrand Factor (VWF) and von Willebrand Disease (VWD), factor VIII (FVIII) and hemophilia A, factor IX (FIX) and hemophilia B, and blood group antigens (particularly ABO and Rh). Variation in blood coagulation (VWF, FVIII, FIX) and bleeding disorders in females, VWF and FVIII changes in pregnancy, female genetic carriers of hemophilia Development of new laboratory approaches in hematology Clinical Interests: Bleeding disorders including von Willebrand Disease, hemophilia, and rare coagulation disorders. Publications My NCBI: My NCBI Bibliography